Endocrine Abstracts

Objectives: Despite the increasing role of molecular profiling, the association between mutation expression and pre-operative cytology for thyroid nodules has not been established.Methods: We collected data on patients who underwent molecular profiling of thyroid nodules in Bethesda categories III to VI from two tertiary academic hospitals and via systematic literature review. We tested the associations between Bethesda categories and molecular mutation ...

Introduction: Thyroid lesions with indeterminate cytology represent about 15% of all thyroid biopsies with the risk of malignancy 15–30%. So the identification of low-risk patients in this group is very important.Few studies evaluated thyroid Tc-99m MIBI [MIBI] scan as a tool for work-up of indeterminate cytology thyroid lesions. The negative predictive value of this test in excluding malignancy appears to be high (95%). But it is not used routinely...

Background: Parathyroid lesion aspiration as a preoperative adenoma localization tool is a matter of controversy. Concerns are being raised regarding both the immediate (hematoma, infection, alterations on a subsequent histologic preparate) and long term (seeding) safety.Objective: To evaluate safety and efficacy of parathyroid fine-needle aspiration (FNA) with parathyroid hormone (PTH) washout as a localization of parathyroid lesions in patients with pr...